Check Part 1 HERE and Part 2 HERE

Implications and practical applications of calorie restriction and intermittent fasting

And now … can the practice of calorie restriction (CR) or fasting have therapeutic value in humans? As noted earlier (Part 1), randomized controlled trials in humans studying the effects of CR and fasting in humans are scarcer. It is not easy to find volunteers to subject themselves to the “discomfort” of eating less food.

Just an aside …
Changing something in someone’s diet can be a daunting task! In fact, and based on my experience, people are generally highly resistant to changing whatever their eating patterns are and tend to defend them tooth and nail! They elaborate the most varied rationales (and very sophisticated sometimes … like the typical “but my grandfather is 90 years old and always ate this and that”) to justify the intake of certain foods that, essentially, they are just used to or like eating. Nutrition is like a religion for some, believe me …!

Back to human studies …
The other practical reason for the lack of controlled randomized human trials on the effects of CR or fasting to study its effects on life expectancy and the incidence of “age-related diseases” is that human life expectancy is long. However, some randomized controlled trials in humans point to clear benefits of CR practice in certain populations. Listed below are some of these studies, type of intervention and significant effects observed.

• Wang et al. (2013)

  • Sample: obese individuals.
  • Intervention: 5 days of 30% CR (low-fat / high-carb or high-fat / low-carb) after isocaloric diet period.
  • Significant results:
    • CR diets decreased fasting insulin and leptin levels by increasing free fatty acid levels (indicating mobilization of fat stores);
    • Insulin sensitivity did not improve significantly (perhaps due to the short 5-day period), however muscle insulin signaling (in response to insulin) increased only in the low-fat / high-carb diet subjects. Note that this effect on insulin signaling in response to the low-fat / high-carb diet (rather than the high-fat / low-carb diet) may represent only a transient adaptive response due to the higher glycemic load in the diet. The short duration of the study does not allow the conclusion of a sustained improvement in insulin regulation.
  • Kitzman et al. (2016)
    • Sample: elderly obese individuals (67 ± 5 years) with heart failure.
    • Intervention: 20 weeks of CR (350-400kcal / day deficit) with or without exercise (1 hour walking 3 days per week).
    • Significant results:
      • Both CR and exercise (separately) increased aerobic capacity (indicated by increase in VO2 peak), with even greater effects if combined;
      • Both CR and exercise (separately) improved body composition (fat loss) with even greater effects if combined;
      • CR (but not exercise) reduced the inflammatory marker C-reactive protein (CRP) and correlated with weight loss.
  • Snel et al. (2012)
    • Sample: obese individuals with type 2 diabetes mellitus (T2DM) and insulin-dependent.
    • Intervention: 16 weeks of CR (450kcal / day) with or without exercise (1 hour + 4 30-minute sessions on a cycle ergometer per week).
    • Significant results:
      • Both CR and exercise improved fasting glucose, insulin and glycosylated hemoglobin (HbA1c) levels;
      • The RC + exercise group lost more fat and waist circumference compared to the CR group only;
      • Both CR and exercise increased insulin receptor expression and signaling (revealed by muscle biopsy) as well as peripheral insulin sensitivity.
  • Pedersen et al. (2015)
    • Sample: overweight or obese, non-diabetic individuals with coronary artery disease.
    • Intervention: 12 weeks of CR (800-1000kcal / day) with or without exercise (3 days / week interval aerobic sled).
    • Significant results:
      • Separately, CR was superior to exercise in weight loss, fat mass and waist circumference, as well as fasting blood glucose, insulin sensitivity and glucose tolerance. However, CR led to better results combined with the exercise program.
  • Razny et al. (2015)
    • Sample: non-diabetic obese individuals
      Intervention: 3 months CR (1200-1500 kcal / day) with or without 1.8 g / day omega-3 fatty acids (in a 5: 1 DHA / EPA ratio).
    • Significant results:
      • CR with or without omega-3 supplementation resulted in similar decrease in body weight and fat mass;
      • CR had a superior positive effect on triglyceride and insulin levels when combined with omega-3 supplementation;

RC + omega-3 (but not only CR) improved indicators of insulin resistance (HOMA index).

  • Prehn et al. (2016)
    • Sample: postmenopausal obese women.
    • Intervention: 12 weeks CR (<800kcal / day) followed by 4 weeks on an isocaloric diet or 16 weeks on an isocaloric diet (control group). Recommendation to increase physical activity per week.
    • Significant results:
      • CR (but not the isocaloric diet) resulted in better scores on memory performance tests;
        CR (but not the isocaloric diet) resulted in improved glycemic control and HbA1c levels;
      • CR-induced increase in cerebral gray matter density was negatively correlated with glucose levels.

Recommendations and Conclusions

In fact, CR or fasting interventions do indeed appear to have clear therapeutic utility in improving health parameters related to obesity, inflammation, insulin resistance, oxidative stress, and cardiac function. It is important to note that just reducing the amount of food you eat may not be enough and perhaps not recommended. Such a simplistic and long-term intervention can result in nutritional deficits and thereby boycott putative positive health outcomes. It is therefore important to monitor and ensure adequate nutrient levels through supplementation and / or in choosing nutritionally dense foods. Also noteworthy are the positive synergistic effects that CR seems to have when combined with exercise (Snel et al., 2012; de Luis et al., 2015; Kitzman et al., 2016), which may be prescribed concomitantly. In this context, a very mild CR intervention (e.g. 10% deficit) or short intermittent fasting periods (> 14 hours and does not need to be daily) combined with exercise may have very positive effects and are likely to have higher compliance compered to more aggressive fasting or CR interventions.

Of course, severe and prolonged CR with no exercise (especially strength training) can induce lean mass loss that is highly undesirable if the goal is to improve health. Once again, and as with almost everything, the secret lies in the right dosage! In certain populations such as pregnant women (or women trying to conceive) and young growing individuals, prolonged CR interventions should be avoided as they may compromise development. However, I emphasize again that the most important thing is not to ingest “calories” but ingest “nutrients”! In older individuals with sarcopenia, CR should perhaps be avoided, although the most determining factors for reversing sarcopenia are strength training and adequate protein intake (which should be higher for older individuals (> 2g / kg bodyweight).

Regarding the specific case of intermittent fasting (note: the focus of this article is not to discuss the use of intermittent fasting as a fat loss and / or maintenance strategy or muscle mass gains in the sports context, but rather its potential for general health benefits) although few, the available randomized controlled trials in humans indicate that intermittent fasting do offer beneficial effects similar to those of constant CR and perhaps is easier to implement (Donati et al., 2008; Marzetti et al., 2009; Alirezaei et al., 2010; Arum et al.; 2014; Godar et al., 2015). Irregular fasting episodes (e.g. not eating breakfast once or twice a week on non-training days) can not only be a strategy easy to implement strategy as a mean to control total weekly calories ingested, and it also has positive hormonal effects is mediated by some of the mechanisms described above. “Hormesis” is defined as a mild stressor that is beneficial to health, stress resistance, growth and longevity. It results from exposure to an “adequate” dose of a stressor. CR or fasting (or exercise) is something that we are evolutionarily designed to tolerate, and which at the right dose gives us benefits and greater resilience. The occasional stress of not eating can be a “healthy discomfort”!

Until next time!

Nuno Correia

Check Part 1 HERE

What mechanisms underlie the effects of calorie restriction or intermittent fasting on longevity and “age-related diseases”?

But after all what is “getting old” … and why …?

Aging has been characterized by several authors as a process of progressive deterioration of molecular, cellular and tissue structures and functions that is conditioned by genetic and environmental factors (Hu & Liu, 2014). This multifactorial and complex process resulting from this progressive loss of function makes the individual more vulnerable to disease and ultimately leads to death. The main determinants (resulting from genetic predisposition and environmental factors) that characterize the aging process at the cellular level have been identified as: free radical damage; mitochondrial dysfunction results in an accumulation of reactive oxygen species (ROS) and consequent oxidative stress; decrease and inefficiency of autophagy (an evolutionarily conserved process of recycling and “cellular waste removal” that is essential for cellular integrity, more details a bit ahead); changes in hormone-related signaling processes such as type 1 insulin-like growth factor (IGF-1), insulin and growth hormone; change in cholesterol and glucose metabolism; telomere shortening (Testa et al., 2014).

Now it seems that the aging process is indeed multifactorial. Probably the various aging theories (see part 1) are correct! In general, molecular processes are becoming more inefficient, slower and the system is progressively moving towards entropy. However, it seems that knowing the autophagy process (whose decline is associated with aging) may offer a “new” perspective on aging. Autophagy (or “self-digestion”) has been defined as an evolutionarily conserved (normal and important) catabolic process characterized by degradation in the lysosomes (cell organelle that functions as a “litter”) of damaged organelles, “defective” proteins and intracellular pathogens (Lavallard et al., 2012). Autophagy provides macromolecule degradation and recycling, not only providing new nutrients and energy during energy restriction (during calorie restriction or fasting), but also preventing the accumulation of cell metabolism by-products and protein aggregates in the cytoplasm. Therefore, autophagy is a protective and essential process for cellular homeostasis (Rubinsztein, Mariño & Kroemer, 2011) (note: rest assured that autophagy will “eat all the muscles” for a few hours without eating. That simply does not happen!). In fact, several authors have pointed deficient autophagic capacity as an important mediator of cellular senescence and consequent occurrence of “diseases or characteristics of old age” such as cardiovascular and neurodegenerative diseases; oxidative stress; weak immune system; chronic inflammation; osteoporosis; sarcopenia; diabetes; obesity; cancer (Pallauf & Rimbach, 2013; Pyo, Yoo & Jung, 2013). Specifically, reviews of mechanistic animal studies have indicated that loss of function in autophagy-related genes has resulted in intracellular accumulation of defective proteins and organelles and consequently in the acceleration of aging, while promoting autophagic activity increased life expectancy (Yen & Klionsky 2008)

(Note: Autophagy mechanisms have been in the mainstream news since 2016 with the Nobel Prize in Medicine 2016 awarded to the Japanese biologist Yoshinori Ohsumi. Their findings in autophagy mechanisms point in the direction that this cellular cleaning and recycling process is essential to prevent neurodegenerative and other diseases. This is the LINK for the news article).

Overall, and since the first rat studies by Dr. Clive McCay in 1935, calorie restriction has been extensively reviewed and recognized as a “potent” anti-aging strategy! Interventions in various types of animal species (from invertebrates to larger mammals such as primates) have shown that calorie restriction (without malnutrition) not only increases life expectancy (average and maximum), but delays the onset of so-called “age-related diseases ”(Martin, Mattson & Maudsley, 2006; Xiang & He, 2011; Lee & Min, 2013; Kitada & Koya, 2013b; Szafranski & Mekhail, 2014; Testa et al., 2014). The intermittent fasting regime (nothing more than another calorie restriction strategy as described in part 1 of this article) seems to offer the same kind of benefits (Martin, Mattson, & Maudsley, 2006; Robertson & Mitchell 2013).

Now the mechanisms by which calorie restriction or fasting induce health benefits appear to be (to a large extent) related to this antagonistic relationship between insulin signaling and autophagy. It is easy to understand, being autophagy a catabolic process (essential, normal and protective, I highlight that again) and the activation of insulin signaling pathways an anabolic process (equally important and essential in protein synthesis, insulin is not the “villain”), when one of these pathways is activated the other will be inhibited. Practically speaking, fasting activates the autophagy “machinery” and eating a meal (mainly containing protein and / or carbohydrates) activates the insulin signaling “machinery”. What seems to be essential is in fact that there are periods that allow the process of elimination and recycling provided by autophagy, and for this to happen it is necessary not to eat for a while. If there is no “room” for this process, due to constant food intake, it may lead to constant and “aberrant” insulin signaling state which may lead to many diseases that are usually associated with poor glucose and insulin metabolism which make the most of the so-called “age diseases”.

(Warning: the “less nerds“ should skip next paragraph)

Briefly, some of the mechanisms identified in animal studies that appear to underlie the health benefits induced by caloric restriction or intermittent fasting through regulation of autophagy and insulin pathway signaling are: 1) Inhibition of insulin / IGF-1signaling (due to the decrease in circulating amino acids and glucose) and its target pathways protein kinase B (PKB) / mammalian target of rapamycin (mTOR) ; 2) Activation of the sirtuin 1 pathway (SIRT1) due to the increase in NAD + / NADH ratio, which targets include activation of adenosine monophosphate protein kinase (AMPK), forkhead box O (FOXO) transcription factors, proliferator- activated gamma receptor-1-alpha coactivator (PGC-1α) (a mitochondrial biogenesis factor), and inhibition of the pro-inflammatory transcription factor NFkB; 3) Activation of the AMPK pathway due to the intracellular increase of the AMP / ATP ratio, which in turn induces up-regulation of FOXO and PGC-1α transcription factors and inhibition of the PKB / mTOR pathway. (Martin, Mattson & Maudsley, 2006; Han & Ren 2010; Rubinsztein, Mariño & Kroemer, 2011; Yen & Klionsky, 2008; Xiang & He, 2011; Pallauf, & Rimbach, 2013; Pyo, Yoo, & Jung, 2013; Hu & Liu, 2014; Szafranski & Mekhail, 2014; Amigo & Kowaltowski, 2014; Testa, G. et al., 2014; Madeo et al., 2015).

In humans, despite the smaller abundance of randomized controlled trials (for the reasons mentioned in Part 1 of this article), several reviews of intervention and observational studies (Yen & Klionsky, 2008; Marzetti, E. et al., 2009; Han & Ren 2010; Robertson & Mitchell, 2013; Testa et al., 2013; Madeo et al., 2015; Fan et al., 2016) indicate that the putative health benefits induced by calorie restriction or intermittent fasting are based on the same mechanisms related to insulin pathway signaling and regulation of autophagy. Some pointed benefits include: longer healthy longevity; better lipid profile; controlled blood pressure; optimization of diastolic and systolic function; better homeostatic control of insulin and glucose; better sensitivity to insulin and glucose; lower incidence of neurodegenerative diseases; lower adiposity; better mitochondrial biogenesis in the skeletal muscle; higher antioxidant capacity; lower levels of ROS and oxidative stress.

Can Calorie Restriction / Intermittent Fasting (CR / IF) alleviate age-related disease by regulating “aberrant” insulin signaling and autophagy?

In conclusion, the effect of caloric restriction or intermittent fasting on the regulation of insulin signaling and autophagy seems to emerge as a central regulatory axis that deserves attention (at least from me).

In the third part of this article I will then discuss what may be practical implications and applications of calorie restriction or fasting. Should we all do calorie restriction? Permanently? For how long? How much? What stage of life? Under what health conditions? Is the “intermittency” factor that delivers the best benefits?

Stay around!

Nuno Correia

References:

Amigo, I. & Kowaltowski, A.J., 2014. Dietary restriction in cerebral bioenergetics and redox state. Redox Biology, 2(1), pp.293–304.

Dröge W., 2009. Avoiding the First Cause of Death. New York, Bloomington. iUniverse, Inc.

Fan, J. et al., 2016. Autophagy as a Potential Target for Sarcopenia. Journal of Cellular Physiology, 231(7), pp.1450–1459. [Epub 2015 Dec 10].

Han, X. & Ren, J., 2010. Caloric restriction and heart function: is there a sensible link? Acta pharmacologica Sinica, 31(9), pp.1111–1117.

Hu, F. & Liu, F., 2014. Targeting tissue-specific metabolic signaling pathways in aging: the promise and limitations. Protein & cell, 5(1), pp.21–35.

Lavallard, V.J. et al., 2012. Autophagy, signaling and obesity. Pharmacological Research, 66(6), pp.513–525.

Lee, S.-H. & Min, K.-J., 2013. Caloric restriction and its mimetics. BMB reports, 46(4), pp.181–7.

Lee, S.-H. & Min, K.-J., 2013. Caloric restriction and its mimetics. BMB reports, 46(4), pp.181–7.

Lindeberg, S., 2010. Food and Western Disease: Health and Nutrition from an Evolutionary Perspective. Oxford, United Kingdom: Wiley-Blackwell.

Madeo, F. et al., 2015. Essential role for autophagy in life span extension. Journal of Clinical Investigation, 125(1), pp.85–93.

Martin, B., Mattson, M.P. & Maudsley, S., 2006. Caloric restriction and intermittent fasting: two potential diets for successful brain aging. Ageing research reviews, 5(3), pp.332–53.

Masoro.E. L., 2002. Caloric Restriction: A Key to Understanding and Modulating Aging. Texas, USA: ELSEVIER.

Pyo, J.O., Yoo, S.M. & Jung, Y.K., 2013. The interplay between autophagy and aging. Diabetes and Metabolism Journal, 37(5), pp.333–339.

Robertson, L.T. & Mitchell, J.R., 2013. Benefits of short-term dietary restriction in mammals. Experimental gerontology, 48(10), pp.1043–8.

Rubinsztein, D.C., Mariño, G. & Kroemer, G., 2011. Autophagy and aging. Cell, 146(5), pp.682–695.

Rubinsztein, D.C., Mariño, G. & Kroemer, G., 2011. Autophagy and aging. Cell, 146(5), pp.682–695.

Szafranski, K. & Mekhail, K., 2014. The fine line between lifespan extension and shortening in response to caloric restriction. Nucleus, 5(1), pp.56–65.

Testa, G. et al., 2014. Calorie restriction and dietary restriction mimetics: a strategy for improving healthy aging and longevity. Current pharmaceutical design, 20(18), pp.2950–77.

Xiang, L. & He, G., 2011. Caloric restriction and antiaging effects. Annals of Nutrition and Metabolism, 58(1), pp.42–48.

Yen, W.-L. & Klionsky, D.J., 2008. How to live long and prosper: autophagy, mitochondria, and aging. Physiology (Bethesda, Md.), 23(70), pp.248–262.

CAN CALORIE RESTRICTION OR INTERMITTENT FASTING HELP PREVENT “AGE-RELATED DISEASES” AND LIVE LONGER? – PART 1

 

Introduction

In this article I will look into the possibility of calorie restriction or intermittent fasting, which is just an alternative strategy to induce a caloric deficit, effective nutritional therapeutic strategies to prevent, alleviate or even eliminate some of the so-called “age-related diseases”, thus contributing for a better and longer life. It is important to note that most studies on the effects of calorie restriction or intermittent fasting (or intermittent calorie restriction) on life expectancy are mechanistic, and conducted in animal and / or in vitro models. It is understandable that there are fewer human intervention studies in this area. If we think about it, it is not easy to conduct studies with humans on calorie restriction to study its effects on life expectancy and the incidence of “age-related diseases”. Not only it is not easy to recruit people to voluntarily incur in a calorie restriction period, it is also not practical to study in humans (in a randomized controlled manner) the effects of calorie restriction or fasting on life expectancy, because they simply “live a long time”. ” In order to obtain timely results, it is essential to conduct studies on species with a shorter life expectancy. However, observational studies and some human intervention studies (discussed later) appear to confirm the same health benefits and molecular mechanisms as those observed in animals.

It should also be noted that, in the experimental context, caloric restriction is defined as “reduced food intake without malnutrition”. In other words, nutritional interventions imply a 10-40% reduction in daily caloric requirements in which only calories, and not nutrients, are restricted (in most controlled studies this is ensured with vitamin and mineral supplementation) (Kitada & Koya, 2013b; Robertson & Mitchell, 2013). This notion is important! Caloric deficit does not imply nutrient deficit and caloric surplus does not imply that nutrient requirements are met. Intermittent fasting will be no more than an alternative method of calorie restriction in which food intake is restricted for a certain period of time (usually 16 to 24 hours) followed by an unrestricted intake period and has been touted as producing beneficial health effects similar to more constant calorie restriction protocols (Martin, Mattson, & Maudsley, 2006; Robertson & Mitchell 2013).

Part 1
Should we accept being “sick” just because we get older?

It is recurrent to hear that the disease is something that “comes with the age package.” In fact, getting older is a drag! The general perception of a progressive decline of all our capabilities as we age is, unfortunately, not an illusion. There are several theories about aging. While certainly a very interesting topic, a detailed description of the various theories of aging is not the purpose of this article. These are some of mechanisms underlying the aging process which are generally pointed out as the main ones:

  • The “Hayflick limit” (phenomenon discovered by Leonard Hayflick) determines that human cells have a replication limit number, after which they become senescent. Telomeres (i.e. a kind of protective “helmets” at the end of each chromosome) become progressively shorter with each cell division (Shay & Wright 2000). However, DNA methylation (an essential and repairing process consisting of the addition of methyl groups to DNA and which can be promoted by the abundance of dietary methyl donors for example) is said to be protective of telomere length and that way to postpone cell death and aging. For example, in animal models, hypomethylation of the enzyme telomerase reverse trancriptase has led to the preservation of leukocyte telomere length (Zhang et al. 2003; 2014). In this example, it is plausible to infer that delaying leukocyte senescence (through methylation and consequent telomere length conservation) may contribute to a stronger immune system and thus positively influence longevity.
  • This theory suggests that unresolved chronic inflammation induces the human organism not to allocate resources for the functioning of other body functions (as they are permanently allocated to unresolved inflammation) and thus leading to early aging of various organs and tissues, and the early onset of “age-related diseases”.
  • This theory, originally proposed by Dr. Denham Harman in 1956, is based on the premise that the aging process is mediated by free radical damage. Theoretically, by reducing free radical accumulation (e.g. reactive oxygen species) and at the same time increasing the antioxidant capacity of the organism (increasing glutathione, and antioxidant enzymes such as SOD and catalase), tissue damage can be prevented (by slowing down aging process) and to prevent the occurrence of “age-related diseases” and consequently contribute to increase functional longevity (Harman, 1988; 2006).

Very well, getting older is inevitable! We already know that. However, if we give it a little thought, all the mechanisms mentioned have an environmental root, that is, we can, to some extent, control them through decisions that we make every day. Namely decisions about what we eat and how we move. And this is good news! It is in fact in our hands to slow down the process of senescence and prevent the onset of the so-called ‘’age-related diseases’’. Note that if for us (Westernized world) it is statistically “normal” to grow old with diabetes, hypertension, cancer, dementia, sarcopenia, osteoporosis, cardiovascular disease, insulin resistance, obesity and chronic inflammation (because the population studied incurs in a lifestyle that leads to disease), in other contemporary (non-Westernized) populations such diseases are rare or even non-existent. In this context, I invite the reader to consult what I consider to be one of the best books I know about nutrition and lifestyle, and its relation to the incidence of so-called “Western” diseases: Food and Western Disease: Health and Nutrition from an Evolutionary Perspective by Staffan Lindeberg. In fact, if we want to aim at maximizing health and lifespan potential, we should not just look at what is ‘’normal’’ in a given population, because that may be a sick population. Rather, we should look for what is “biologically normal” for a human being! A species that is designed (evolutionarily) to deal with a range of environmental stimuli that include certain levels of physical activity, nutrition, sun exposure and sleep. And, although aging is a normal process, it should not be “biologically normal” to age with chronic disease.

In this context, the Okinawa Centenarian Study is also frequently cited. The Okinawan population has the highest ratio of (healthy) centenarians on the planet (50 / 100,000 vs 10-20 / 100,000 in the USA) and as such is of greatest interest to study the factors that potentiate this kind of longevity. One of the factors identified (in addition to an appreciable level of physical activity and social interaction) was the fact that populations over 70 eat about 11% of calories below (about 1785kcal / day, which is a very moderate level of calorie restriction) than would be recommended for maintaining body weight (according to the Harris-Benedict equation), however on a nutrient-rich diet (Wilcox et al., 2006).

*Okinawan residents expected to have the highest ratio of centenarians worldwide with 50 / 100,000.

What we can do to live longer and better is one of my main interests. As I mentioned, our choices regarding the type of exercise, food we eat and other lifestyle factors can affect how long we live and, perhaps most importantly, how healthy and functional we live. In Part 2 of this article I will discuss some mechanisms by which nutritional interventions such as calorie restriction or intermittent fasting can lead to health benefits. And in Part 3 I will address the possible implications and practical applications of the practice of calorie restriction or fasting, as well as which populations can benefit most from these nutritional strategies and whoshould avoid them.

Stay around!

Nuno Correia

References

Dröge W., 2009. Avoiding the First Cause of Death. New York, Bloomington. iUniverse, Inc.

Harman D., 1988. Free radicals in aging. Mol Cell Biochem. Dec; 84(2), pp.155-161.

Harman D., 2006. Free radical theory of aging: an update: increasing the functional life span. Ann N Y Acad Sci. May;1067, pp.10-21.

Kitada, M. & Koya, D., 2013b. SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential. Diabetes & metabolism journal, 37(5), pp.315–25.

Lindeberg, S., 2010. Food and Western Disease: Health and Nutrition from an Evolutionary Perspective. Oxford, United Kingdom: Wiley-Blackwell.

Martin, B., Mattson, M.P. & Maudsley, S., 2006. Caloric restriction and intermittent fasting: two potential diets for successful brain aging. Ageing research reviews, 5(3), pp.332–53.

Masoro.E. L., 2002. Caloric Restriction: A Key to Understanding and Modulating Aging. Texas, USA: ELSEVIER.

Robertson, L.T. & Mitchell, J.R., 2013. Benefits of short-term dietary restriction in mammals. Experimental gerontology, 48(10), pp.1043–8.

Shay J.W., Wright W.E. 2000. Hayflick, his limit, and cellular ageing. Nat Rev Mol Cell Biol. Oct;1(1), pp.72-76.

Zhang D. et al., 2013. Homocysteine-related hTERT DNA demethylation contributes to shortened leukocyte telomere length in atherosclerosis. Atherosclerosis. Nov; 231(1), pp.173-179.

Zhang D.H., Wen X.M., Zhang L. & Cui W., 2014. DNA methylation of human telomerase reverse transcriptase associated with leukocyte telomere length shortening in hyperhomocysteinemia-type hypertension in humans and in a rat model. Circ J. 78(8), pp.1915-1923.

Wilcox D.C. et al., 2006. Caloric restriction and human longevity: what can we learn from the Okinawans? Biogerontology  7, pp.173–177.

Strength training has been recognized as the strategy of choice to stay more functional and live longer. The benefits of strength training are in fact ubiquitous and positively affect the various biological systems that tend to decline with age, namely systems related to neuromuscular, cardiovascular and cognitive functions.

It has been observed that strength training programs in which the included exercises are performed at higher intensities (> 80% of maximum intensity) or with lighter loads but performed explosively tend to produce better results compared to training protocols where exercises are performed at lower intensities and / or non-explosively (Mendonça et al., 2016a). The magnitude of the load used (i.e. heavy or lighter but performed explosively) are especially relevant for older populations. Why? Because aging is associated with the loss of Type II muscle fibers, which are responsible for producing maximal strength (e.g. lifting a weight and not being able to lift it again in the next minutes or hours) or as explosive strength (e.g. moving an object or your own bodyweight at maximal speed). Now, the overwhelming majority of daily life movements are ballistic in nature (i.e. fast, short duration movements) and often for the purpose of moving relatively heavy objects for a short period of time. Therefore, it is not surprising that a training program that includes exercises that imply moving heavy loads and / or loads moved explosively is more effective in “preparing” people for everyday activities.

Training at higher intensities in a training program based on fundamental movement patterns (squatting, pushing, pulling, loading and lifting objects off the ground) makes people less vulnerable to falls and “tweaks”, and at the same time more able to recover from such incidents should they occur.

Train hard and smart! A structured training program that respects the principle of progressive overload is more valuable than a program that always keeps you within the comfort zone. Be as active as you can get during the day but IF TRAINING AT GYM DO NOT WASTE YOUR TIME, AND REALLY TRAIN! Seriously, it works!

Good lifting! ?

References

Mendonca, G. V. et al., 2016a. Impact of Exercise Training On Physiological Measures of Physical Fitness in the Elderly. Current aging science, 9(3).

 

Following up on the topic addressed in the last article, let’s talk today about a common swing characteristic that affects a lot of golfers and that can compromise their swing efficiency and their performance on the golf course: Early Extension.

What is Early Extension?

Early extension can be understood as an integral part of loss of posture, this happens when the player’s hip and spine begin to extend too early in the downswing, i.e. the hips and pelvis move towards the ball in the downswing. In practical terms, if your body is not prepared to perform an efficient golf swing while maintaining good posture throughout the movement, you will end up lifting the upper body (spine) and miss the necessary hip rotation at impact. Your hips play a key role in injury prevention and performance improvement. If you have poor hip mobility, sooner or later your lower back will complain (and you can be sure that this situation will not be very pleasant).

According to studies conducted by the Titleist Performance Institute, 64.3% of amateur golfers early extend

Players who early extend usually refer that they feel trapped during the downswing as if they had to shrug their arms to hit the ball. And it’s normal for that to be so because when you extend your hips too early on the downswing, the space that was supposed to be occupied by your arms and hands was occupied by the lower body. Therefore, the end result will be a blockage of the movement, since your arms and hands can’t get out of the way and will still be needed to hit the ball.

How can I diagnose?

An easy and simple way to check if you do early extension is with your Smart Phone (you probably already have applications that allow you to draw lines and analyze your swing). All you need to do is to ask a friend to film you in the direction of the swing line and capture its full motion from the starting position (setup). After having your swing recorded, compare the position of your pelvis in the initial position with the position of the pelvis in the position of impact, if you notice that it moved towards the direction of the ball is because you extended your hip too early. If this is not possible, you can always ask your golf teacher to help you, I am sure he will be happy to do that.

What are the physical limitations?

“If you’re not assessing, you’re just guessing” – Greg Rose

The physical limitations can be many and to determine the causes that are affecting you, it would be important to make a functional assessment with a professional who understands how your body should move and its relation to the golf swing. According to what I have observed in my practice, I would like to highlight the following:

  • Limitations on performing a full squat with the arms extended overhead;
  • Limitations in hip mobility (especially in internal rotation of the leading hip and in anterior or posterior pelvic tilt);
  • Limitations in the ability to separate / disassociate the thorax from hips (X factor);
  • Limitations in the ability to stabilize the pelvis because the glutes and core muscles are inhibited.

What can I do to improve?

Although the causes may vary from person to person, I’m pretty sure that if you do the following exercises, you will improve and increase your body’s functionality to play golf for a longer time. You only need 10 minutes a day.

  1. Myofascial Release with Roller Stick

Using a roller stick, look for the trigger points of your calf and massage the inner, central and outer sides of the muscle for 30 seconds in each area. The points that hurt you most are those that need more care. Yes, this exercise might be a little uncomfortable but it’s worth it.

  1. Glute Bridge with Leg Extension

Lying in the supine position, push your heels against the floor, tighten your glutes, and raise your hips to form a glute bridge, with your arms up. Once in this position, extend one leg and form a straight line between the shoulder, hip and heel. Hold this position for 20-30 seconds, always keeping your hips high. Change legs and repeat 5 times on each side.

  1. Squat with Overhead Arm Reach

In the squat position (with your heels on the floor and your knees out), raise one arm up, lift the other arm (always looking at your hand) and then raise both arms at the same time and return to the standing position. If you can not squat without raising your heels, you can use a rolled up towel or a board to keep your heels high. Do 2-3 sets and repeat 8-10 times.

  1. Assisted Squat wiht Medicine Ball

In the standing position, with your feet shoulder-width apart and slightly rotated out, hold a medicine ball (or a bucket full of balls) in front of your body, and begin to slowly lower your body into the squat position by keeping your back straight and without lifting your heels off the floor. Do 2-3 sets and repeat 10-12 times.

I believe that these exercises can be helpful to you, but remember: The swing you can do is directly related to what your body is prepared to do.

See you soon!

Pedro Correia

 

“Do not judge a man’s strength by the size of his biceps. Things do not always look what they seem.”

– Pavel Tsatsouline

In my opinion a normal human being should aim to be strong. And when I say strong, I’m not talking about those bulked individuals with a strange gait. Anyone (of any age) can become stronger by working consistently for this. Unfortunately, most people are more WILLING to be strong than doing what they need TO DO to be strong. Yes, these are different things. And yes, it’s not easy. One thing is WANTING a top-of-the-range Porsche, another thing is DOING the things needed to have a top-of-the-range Porsche. With strength is the same situation. To be strong, you need to have a plan (or have someone design a plan for you) and to work consistently to execute that plan – this is what your objective should be: to execute the plan. That’s it. You do not become what you THINK about every day, you become what you DO every day. Yes, there are no miracles, no one gets stronger without effort and without spending the time necessary for that to happen. The fitness magazines and the marketing associated with this industry want to make you believe that it’s possible to get stronger or leaner without great effort and quickly. It’s because of these kinds of messages that people still believe in shortcuts and / or allude to the power of genetics. They want it all but they don’t do anything (nothing useful at least). And then they still blame genetics!

There is one thing you should be aware of right now, strength is a skill. And in this sense, strength is the ability to generate more tension in muscles. And that is why strength is the basis for the development of speed, endurance and even flexibility. Like all skills, there are techniques or more appropriate ways to develop it. And that’s what I’m going to share with you. I will teach you some techniques for you to get stronger faster but this will only work if you apply them consistently in training. So, do them! Some of these techniques have already been used with me and with my clients / athletes, so I can assure you that they work and that they are scientifically proven, if that interests you as well. And before explaining them, I want to refer to Pavel Tsatsouline (I love reading his books), since he has been one of the individuals who has shared most of the “Russian secrets” of strength and one of the persons who have inspired me most in this journey. I hope I can meet him someday. Ready? Let’s do it!

  1. Irradiation

This one is easy, this one any five-year-old understands.

First make a bicep curl set of 5-6 repetitions with good form, keeping the elbow close to the body and without tilting the trunk back. You can use a dumbbell or a barbell. But a serious dumbbell, it’s not worth using Barbie and Ken-style dumbbells, let these tools for people to have fun in aerobic classes! After doing this set, rest for a few minutes and make the following changes: before doing the movement again, i) squeeze hard the dumbbell or barbell; (ii) squeeze your glutes as if you wanted to crack a nut with your buttocks and (iii) tighten your abs and imagine that Mike Tyson will punch you in the stomach.

If you can do these three things, you will realize that the weight will get lighter and you will be able to do a few more reps – in a better and safer way. The explanation is this: when you create tension at various points in the body this will increase total body stability (via the neural impulses produced by the contracting muscles) and this stability / force will irradiate (i.e. spread) to the neighboring muscles as if it were an electric current to start the engine. And the most interesting part lies on the fact that the strength of a particular muscle, for example the bicep, can be amplified if the neighboring muscles also help! Have you realized why in the union lies strength? The formula is simple: more tension = more stability = more force.

  1. Bracing

Who still does arm wrestling in school? I perfectly remember the times when I was in school and this was one of the games we did in during class breaks or when we had a hole in our schedule. I remember very well the agonizing look of my classmates when they were about to be defeated or their expression of jubilation when I let them gain advantage and then finished strong. Yes, this was fun at the time! And yes, most of the time I won ?.

I gave the example of arm wrestling because I think this is the best way to understand this phenomenon. Lets’ see: an individual who can generate more tension before squeezing his opponent’s hand will have a superior neuromuscular activation level and a clear advantage over an individual who only begins to squeeze when someone (the referee) gives the signal to begin the “combat”. According to Prof. Yuri Verkhoshansky, if we create a sort of pre-tension in the muscles before starting a dynamic contraction, this can lead to increases of up to 20% in performance! Now imagine the advantage you can have if you can apply this technique and if your opponent does not know about it.

Try this technique as follows. Do five normal push-ups and relax on the floor between reps. Then do another five and this time think about creating tension in the whole body, that is, think of squeezing your glutes and abs before pushing against the floor to come up. If you do this well, you will realize that you are much stronger than you thought. Therefore, the key to this technique is in creating tension in the whole body before counteracting resistance. If you do not create this tension before, you will remain weak. Do not be that person.

  1. Power Breathing

First, a few notes on breathing. Proper breathing is very important to maximize performance, a normal person breathes on average more than eight million times a year and it is more likely that he will not do it efficiently. If there was a movement pattern that you had to repeat 23,000 times a day, would you not make an effort to improve it? Think about this a little bit. Most people only use a small percentage of the body’s ability to extract oxygen from the air into the lungs because they tend to breathe only with the upper body (apical breathing), instead of breathing deeper by using the most efficient respiratory muscle we have, the diaphragm (I think we do not talk much about the diaphragm in fitness / bodybuilding magazines because this is an invisible muscle that will not really impress women). But the fact is that this daytime breathing will affect several things: your recovery ability, your anatomical structure, the functioning of your autonomic nervous system, and your cognitive ability. So, if we are talking about performance optimization, be sure to improve your breathing patterns as well.

Second, regarding power breathing, this technique consists of holding the breath during the various phases of lifting. For example, the legendary Bruce Lee used to say that in the martial arts the power of breathing was more important than body strength. In general, the effect of breathing patterns and intra-abdominal and intra-thoracic pressure on strength is strangely ignored or misunderstood by fitness professionals and some medical authorities. These authorities seem to forget that orthopedic injury is much more common than cerebrovascular injury. That traditionally taught breathing pattern of inhaling when we lower the weight (eccentric phase) and exhaling when we raise the weight (concentric phase) may be useful in some cases (and we can’t say that’s wrong) but it’s not the one you want to do when you want to generate as much tension / strength as possible in the muscles. Why? Because the increase in intra-abdominal and intra-thoracic pressure will boost muscle excitability (through the pneumo-muscular reflex) and it is this process that will guarantee more stability in the spine and that will amplify your strength. This is the most natural way to produce strength! Yes, your fitness instructor may have said that forced exhalation of air against the glottis (i.e. the Valsalva maneuver) is hazardous to your health and that you may have a stroke doing this. But is this assertion correct? Prof. Yuri Verkhoshansky and Dr. Mel Siff, two of the world leading authorities on strength training, say the following in this regard in the book Supertraining, one of the strength training bibles:

“For example, the Valsalva maneuver associated with holding breath has a vital role in increasing intra-abdominal pressure to support and stabilize the lumbar spine during heavy lifting… It has been corroborated on many occasions that stress on the spine is decreased during any movement against high resistance and that exhalation during lifting increases the risk of injury to the lumbar spine. Thus, it is unwise to follow popular medical advice that people must exhale during the effort”. The authors further add: “while this may be appropriate for patients with heart disease or hypertension, this same action performed by an athlete who is doing squats or heavy lifting overhead, can seriously compromise spine stability and safety”.

Got it? This means that any healthy person can and should apply this technique if they aim to get stronger and lift heavy loads in a safe way. People with hypertension and heart disease should be more cautious in this regard but please note: this is not to say that they can’t strength train, there are many other ways to develop strength. By the way, it is already well documented in the scientific literature that these people can and should do strength training to improve their condition!

  1. Successive Induction

Successive Induction, such as the Law of Irradiation we have seen above, is another of the Sherrington Laws exploited to the maximum by the Russians. According to this law, contraction of a muscle – for example, the triceps – will make your muscle antagonist – in this case, the biceps – stronger than normal. In the early 1980s scientists suggested that this technique had a disinhibiting effect and later confirmed that a strength training program that included pre-tensioning an antagonist muscle (i.e. successive induction) was more effective than a program of conventional training. And the most interesting thing is that these benefits were not only limited to an acute performance increase, but also resulted in long lasting strength improvements.

Do the following test. Grab a barbell or free weight and get ready to make a bicep curl set with a load that allows you to do 5-6 solid repetitions. Remember, hold your elbows close to your body and do not lean your trunk back. Do one set and count the number of repetitions you can do with good form. After resting for a few minutes, keep the same weight and do another set, but this time using this new technique. When you bring the weight up, apply the other techniques you already know (irradiation and bracing) and on the descent apply the technique of successive induction, “pulling” the weight down with the triceps. In this way, you will give the biceps some rest on the descent (by preventing them from locking the movement) and will allow the triceps to also have a more active participation in the movement. You should expect to be able to do one or two more reps this way!

Therefore, when applying this technique, you will have two engines controlling the movement. And because of the co-contraction of both muscle groups, this technique may also offer greater benefits in terms of joint stability since the stress on them will be reduced (note: do not forget to discuss this with your doctor if you have joint problems).

Finally, my advice to you is this: if you want to start lifting heavy loads safely begin applying these principles in training (if you can’t do this alone ask someone you know to help you) and enjoy learning one of the skills (i.e. strength) you will need most to optimize your health. And be patient, do not expect to learn all these things from one day to another – it takes time and practice, good practice of course.

See you soon!

Pedro Correia

References

Tsatsouline, P. (1999). Russian Strength Training Secrets for Every American. Dragon Door Publications.

Tsatsouline, P. (2003). The Naked Warrior. Master Secrets of the Super Strong – Using Bodyweight Exercises Only. Dragon Door Publications.

Verkhoshansky, Y; Siff, M.; (2009). Supertraining. Sixth Edition – Expanded Version. Ultimate Athlete Concepts.

Verstegen, M.; Williams, P. (2014). Every Day is Game Day. Penguin Group.

 

“We don’t believe there is one way to swing a club; we believe there is an infinite number of ways to swing a club. But we do believe there is one efficient way for all golfers to swing a club and it is based on what they can physically do.”

– Titleist Performance Institute

If you’re reading this, you’re probably interested in improving your physical condition to make more birdies, hit longer drives, and increase your longevity as a golfer. Or, perhaps, your goal is to become the best player in your club or win the next Match Play Championship. No matter what your motivation is, the fact is that if your goal is to improve your game, this will require you to prepare yourself a bit better than most golfers I know. And better does not necessarily mean training longer hours!

If you´re still one of those players who spends hours and hours hitting buckets of balls on the driving range hopping that this will help you improve your golf game, you need to change your strategy. Hitting buckets of balls in the driving range and making chips and putts is not enough. If you truly want to improve your performance in this sport, your practice needs to include general athletic development exercises and specific physical training for golf, in a progressive and periodized manner.

This means that what you normally see in the gym has nothing to do with what you need to do to hit farther, straighter and to go through the 18 holes without getting so tired.

First: Is your swing efficient?

The only way to determine whether your golf swing is efficient or not is through a 3D Biomechanical Analysis. What we can see in the traditional video imaging used by most golf professionals / teachers is just the swing style. There are many golfers who do not have a particularly attractive swing (e.g. Raymond Floyd, Jim Furyk or John Daly) but the reason why these players were or are successful is because their swing is efficient. Having an efficient swing for a golfer means transferring energy (without leaks) through the feet, knees, hips, spine, shoulders, arms, wrists down to the club head and ultimately to the ball. With the data obtained through the 3D system, we can check the kinematic sequence of each player, that is, we can measure the speed of rotation of each body segment involved in the execution of the golf swing and determine if each segment is accelerating and decelerating correctly.

When we look at Jim Furyk and Ernie Els swing through video analysis (and through the naked eye), we can see that both swings are quite different from each other, however, when we look at the kinematic sequence of each player, we find that it’s difficult to see a significant difference between the two swings. This means that although Ernie Els and Jim Furyk have completely different swing styles, they both share the same kinematic sequence.

All great players start by generating speed from the hips and transferring that energy through the torso, arms and club. This is the efficient sequence in the downswing.

The golf swing is a complex multi-dimensional movement that involves a highly coordinated action of the entire kinetic chain (feet, knees, hips, spine, shoulders, arms and wrists) and takes less than two seconds. The golf swing is therefore a ballistic movement which, in order to perform efficiently (i.e. with a correct kinematic sequence), it’s necessary that the various body segments are properly prepared to deal with the inherent shear and rotation forces in this movement. Hence the importance of what follows.

Second: The Physical Assessment in Golf

Before we get to the physical training itself, it’s important to know what your physical limitations and asymmetries in terms of movement are (one of the main causes of injury). Because of this, it’s essential that you perform a functional assessment for golf, preferably with a qualified professional that knows what he’s doing. In the same way that you go to the doctor for exams to find out how your health markers are, you should also do an initial assessment with a golf fitness specialist to find out how your body behaves during a golf swing and which are the main limitations / compensations.

The physical evaluation in golf consists of performing several tests in order to measure the functionality of the body movement patterns necessary for golf, that is, the measurement of various indicators of its stability, mobility, balance and various performance parameters such as strength, power and cardiovascular capacity.

This type of assessment is the starting point for playing better and for preventing injuries. If you still think that your body is fine and that you don’t need any intervention at this level, you’re more likely to be wrong. Our body was not designed to lead the way we live today, so you can be pretty sure there are things in your body that need some work. If you still do not believe me, think of golfers you know who have never complained of back pain or pain in another part of the body (wrists, shoulders, elbow).

Your body is the determining piece of equipment in your game. The quality of the clubs, balls, gloves, shoes and the latest drive or putt on the market, are certainly not the most important aspects. I still see many golfers too preoccupied with the new gadgets and the style of clothing, when in fact these are not the most important things to get more birdies. What will, in fact, bring you better results is improving your body’s functional skills to hit the ball more efficiently and safely.

Final Remarks

Many players fail to perform an efficient golf swing not only because the movement itself is complex but also because their bodies are not properly prepared to deal with the forces generated during the movement.

Keep this in mind the next time you hit balls or have a lesson with your golf teacher, maybe that’s why you can’t do what your teacher asks you to do. There is no point constantly insisting on improving technique if there is no synergistic effort in improving physical skills. The swing you can perform is directly related to what your body is prepared to do – think of the golf club as an extension of your body.

In the next articles I will share the most common characteristics in this relationship between the body and the golf swing and suggest some exercises so that you can improve your performance on the golf course.

Stay tuned!

Pedro Correia

 

If you still exercise to “burn calories,” you have not yet realized the purpose of a physical training program and the importance that movement has in our lives. The least important thing about exercise is the number of calories you burn! And that’s what I’ll try to explain in this article.

The power of exercise goes far beyond calorie burning, caloric expenditure is just a (nice) side effect of the type of exercise we do. Exercise consists of potentiating the release of powerful molecules and hormones that “talk” to our body’s organs (it’s not just food that has this kind of influence), and that determines what’s going to happen. And usually, the higher the intensity, the more beneficial the hormonal response.

Therefore, a well-designed physical training program has more to do with increasing energy levels, movement precision, vigor, muscular strength, mobility, agility, speed, work capacity and with an improved hormonal profile.

The Calorie Fever

I still see a lot of people worried about the calories in their food, the calories they burn when they exercise, the calories they consume each day, and I ask: How did we get here? What kind of message is being propagated that made people so obsessed with calories? Is calorie counting that important? Let’s see.

In order to discover the amount of energy in food, scientists burn food samples in a bomb calorimeter. And, to my knowledge, a bomb calorimeter does not share the same physiology and genetic makeup as a human being. As far as I know, a bomb calorimeter does not depend on the functioning of the various systems in the human body which are the real players in the way energy is absorbed and used (examples: digestive, endocrine and nervous system). This way of thinking is most likely unsustainable and ineffective long-term. This way of thinking is too reductive and does not solve the main problem – people’s lack of education regarding the importance of what we eat throughout our lives. Is it just me who finds it strange that most people are more concerned about their cell phones, cars and computers than with the origin and composition of the food they eat?

In fact, just look around and you’ll acknowledge that this is not the path to follow!

It is true that if we have the goal of losing fat mass, we must create an energy deficit, that is, the balance between the amount of calories (energy) entering our body and the amount of energy (calories) burned, must be negative. That’s the number one rule in rigid weight loss programs and that’s why we see Biggest Loser contestants training several times a day.

(Note: I should remind you that the Biggest Loser is a contest in which the goal is to lose weight in the shortest time possible, it’s not a contest to see who gets out of there healthier – if this was the goal probably there was no audience).

However, there is a lot more to be said. There are good calories and bad calories. The foods we eat, besides having a certain number of calories (which can be very difficult to determine with accuracy and can be highly variable), also have different properties with respect to their composition of macronutrients (protein, fat, carbohydrates) and micronutrients (minerals, vitamins, phytochemicals). These bioactive properties and compounds are what makes the difference and what should be studied preferentially. In my way of looking at things, it is more logical to first check the functionality of food (i.e. how its nutrients work) and then look at its caloric density, which can also be more or less functional depending on the objectives, morphology and specific conditions of each individual.

(Note: If you still think low fat diets are the most suitable for weight loss check the following study published in 2003 in the New England Journal of Medicine here, where it was shown that people on a high-fat diet lost more weight as those on a low-fat diet, the diet generally recommended by leading health organizations. But, of course, adherence to the diet will be the most important factor).

Back to calories…

Because the absorption of these nutrients will depend on the functioning of our digestive system – which in turn is governed by the endocrine system (think of hormones) and the nervous system (think of neurotransmitters) – and the health of the organs involved in the digestion process (mouth, esophagus, stomach, pancreas, small intestine, large intestine, liver, gallbladder), it becomes easy to understand that the web of relationships in the human body is much more complex than simple calorie counting. Albert Einstein has a quote that fits perfectly here: “make everything as simple as possible, but not simpler.”

The Power of Exercise

Anyone that is minimally informed about exercise already knows that long distance aerobic training is not the best choice for improving body composition and may even have opposite effects (catabolic effects) due to the pronounced increase in cortisol levels.

This has been known for a long time but it’s always important to remember. This study published by Tremblay, Simoneau and Bouchard in 1994, showed that the group that did 15 weeks of interval training burned NINE TIMES more fat than the group that did aerobic training. And this was in half of the time period!

What you need to “burn calories” is to increase the intensity of your workouts for certain periods of time, it’s this type of stimulus that will increase your metabolism and accelerate fat loss. In this study, a 30-minute training session of metabolic resistance training caused a 38-hour increase in metabolism – the famous afterburn effect or EPOC (post-exercise oxygen consumption). Let’s put this into perspective. Let’s say you trained this way on Friday morning. With this training method your body will still be in a “fat burning” mode on Saturday night, when you’re having dinner with your friends or with your boyfriend / girlfriend.

And why do I insist on combining a good diet with good training? Because I’m aware of the evidence on this topic. This study  from 1999 showed that those who did aerobic training and strength training on a low calorie diet burned 44% more fat than those who merely followed dietary guidelines. As I’ve been saying, diet is the most important component for those people who want to lose fat, however, once that aspect is assured, only strength training and interval training can actually bring your results to a higher level. In my opinion, the fact that this study was based on a low-calorie diet combined with aerobic training is limiting, but we have to bear in mind that these are usually the guidelines of the American College of Sports Medicine (ACSM). The guidelines are intended to facilitate nutritional guidance offered by practitioners, but unfortunately that is not what I have observed when I discuss these issues with some colleagues.

I think you have already realized that the type of training you do can be a great ally to put your body in an energy deficit and consequently in fat burning status. Now I will try to explain why this is the least important of all. Stay with me!

Like nutrition, physical exercise is key to improve health, performance and body composition. You’re probably tired of hearing this. But it’s not any kind of physical exercise that works. Doing hundreds of crunches to lose belly fat, using all the gym machinery, running 10 miles a day, doing Pilates twice a week and doing 100 power cleans in the shortest time possible is not enough. You can call it physical exercise if you want, but it’s not just this kind of physical exercise our body needs. A more comprehensive approach is needed.

We need Good Movement (we shouldn’t start running in the first place)

The concept of “move more for your health” is insufficient for our real needs and to improve quality of life. We need good movement, we need to acquire movement competency in the first place. I am talking about the ability to perform fundamental movements with good form. Fundamental movement patterns such as squatting, hinging, pushing, pulling, throwing, carrying, walking, running and jumping.

 

 

From my point of view, running should be the last step in this process and yet what we most frequently see is people running all crooked and with an obvious deficit in muscle strength. But the problem is not theirs, they are trying to do something for their health (and probably that’s all they know), the problem is that most of them are not aware that running is a skill, which requires preparation, practice and training. Cristiano Ronaldo did not become the best player in the World over night, it took many hours of training (in the field and in the gym) to reach this level. Although it’s relatively easy and affordable for anyone to put on their shoes and just go out for a run, running also requires preparation, practice and training (technical and physical).

It is necessary to have stability, mobility, strength (every step we take on the ground is subject to the action of gravity and the speed we run, generating reaction forces of 2 to 5 times our body weight), symmetry, quality of movement and good musculoskeletal health. Running to get healthy or fit is one of the greatest physical distresses on our body if we don’t have a solid foundation. First, you need to be in good shape to run. If you don’t hone good movement skills, you are more likely to get injured. According to the available literature, the incidence rate of injury in runners may exceed 90%, this is more than any other sport. Plantar fasciitis, stress fractures, patellar tendonitis and patellofemoral pain are just a few examples. Check this systematic review if you’re interested in learning more.

Again, don’t get me wrong, I’m not anti-running and I admire the effort and suffering capacity of all runners. I think we should all be able to run (by the way, that’s how we evolved as a species), the problem is that most people who run are not properly prepared to run and there are fundamental learning steps that should not be overlooked in order to prevent structural imbalances in the musculoskeletal system and injuries. Cleary the simplistic idea of “move more” is not enough.

A new way to look at training

Different types of training can affect the way our genes work and how they interact with our cells. With good training it’s possible to decrease chronic inflammation, improve insulin sensitivity, strengthen the cardiovascular system, improve lipid profile, slow down normal aging, burn fat (as we’ve seen in more detail above), increase confidence and self-esteem, increase energy levels, increase mental strength, improve a number of physical skills that we need for our daily life activities or sports practice (such as strength, stability, mobility, balance, speed, agility) and our different energy systems (ATP-CP, glycolytic, and oxidative). As we age, these skills naturally decline, but the fact is that with a more comprehensive training program it is possible to reverse and / or at least mitigate this decline.

Most people think that genes are the brain of the cell, they believe that if genes don’t tell you what to do, the cell dies. But if you remove the genes from the cell, the cell is still alive, eliminating waste products and behaving just like another cell. So, instead of genes being the brain of the cell, think of genes as your instruction / repair manual. When a worn part of the cell needs to be repaired or when new substances need to be produced, genes will give instructions for doing so.

Every cell in our body is surrounded by a fatty membrane, which is filled with thousands of receptors. These receptors receive information from different parts of the body and pass this information into the cell to form / encode new proteins, burn more or less fat, etc. (Note: this is why it’s important to eat good fats and avoid the hydrogenated fats present in most processed foods so that the cell membrane is more permeable to nutrient delivery.) It’s this membrane with receptors the cell command center so if we remove these membrane receptors, the cells die. This means that cell function is highly influenced by external factors, namely through hormones and other molecules that bind to these receptors.

These messenger molecules are not randomly created by our body, they are created according to our lifestyle, diet, thoughts, behaviors, temperature, light, sound and… our type of training. It’s possible to be born with some defective genes – for example BRCA 1 and BRCA 2, which increase the risk for breast cancer – but it’s these messenger molecules / hormones that will determine the degree of activation of these genes. Therefore, controlling these hormones means controlling the body.

(Note: Don’t you find it strange that almost 90% of health care costs is related to treat health conditions, while 80% of health problems / diseases arise as a consequence of our lifestyle and the environment we’re exposed to? Check this TED talk from Dan Buettner to realize why we are walking in the wrong direction).

High-intensity exercise is the one that induces a more favorable hormonal environment, with an increase in hormones such as testosterone, growth hormone and IGF-1, interleukins with an important role in inflammation (IL-6), muscle tissue maintenance (IL-15) and growing of new blood vessels (IL-8), lactic acid (which has the ability to keep us young by stimulating the release of testosterone and growth hormone) and nitric oxide, a vasodilator which plays a key role in regulating blood pressure, muscle strength and erectile dysfunction. Unfortunately, long running does not produce the same effects. Compound movements, which require a combination of strength and stamina, in short periods of time, are those that will put your muscles to “talk” more with your body. Burning calories is only a minor side effect when compared to the amount of hormones and other signaling molecules that influence how our body works.

To be clear, we are talking about intensity coupled with movement quality. Intensity coupled with bad movement will have the opposite effect: INJURY.

Conclusion

It’s urgent to give rise to a new mentality on training the movement skills that we will need throughout our lives. And this is a serious limitation of most group classes in conventional gyms. The instructors are obliged to follow a certain beat and choreography. Individualized feedback is almost non-existent. People don’t have time to understand or to learn the movements. And no one learns anything if they don’t know what it’s for, no one learns anything if they don’t understand how it’s supposed to feel and its practical implications. In addition, most machines in gyms annihilate the sensory and body perception that we, humans, need. We live in a three-dimensional world, in a world of constant adaptation and spatial exploration, so it makes no sense that machines and choreographies of group classes dictate the rules of our movement.

And why is it important to learn efficient movements? First, an efficient movement happens when a body is able to produce force through a coordinated action between the various body segments without energy leaks and demonstrating a natural ability to exploit maximum range of motion. Second, it’s movement that will allow you to play more time with your children, change the furniture at home, improve your day-to-day performance and your performance in your recreational activities.

Look at this type of training as the foundation, the support you need to get stronger, faster, smarter, more agile, more competent in a series of physical attributes that will allow you to perform better in the activities you enjoy doing. Would you like to start playing tennis? golf? volleyball? Would you like to start surfing? paddle board? weightlifting? powerlifting? dance? climbing? triathlon? Would you like to be faster when you play football with your friends during on weekends? Obviously, each modality has its specific abilities, but they all share the same foundation: human being’s adaptability capacity. To improve these specific skills safely, you first need to improve your fundamental movement patterns. And to sustainably keep improving these fundamental movement patterns, you need to train better and respect the developmental stages of each one.

To sum up, the great advantage of better training (and I remind you what we learned about the power of exercise, good movement and a new way of looking at training) is to improve your quality of life, maximize your performance and, above all, giving you the freedom and autonomy to choose the activity / sport that you always wanted to try but never had the courage or opportunity to start off.

Think about these things next time you go to the gym to walk on the treadmill with your headphones on and watch some TV series for 40 minutes while looking at the calories burned on the monitor and at the workouts or exercises other people are doing.

See you soon!

Pedro Correia

References

Berardi, J, Andrews, R. The Essentials of Sport and Exercise Nutrition. Certification Manual. Second Edition. Precision Nutrition Inc. (2013).

Björntorp P. Hormonal control of regional fat distribution. Hum Reprod. 1997 Oct;12 Suppl 1:21-5. Review.

Frederick F. Samaha, M.D., Nayyar Iqbal, M.D., Prakash Seshadri, M.D., Kathryn L. Chicano, C.R.N.P., Denise A. Daily, R.D., Joyce McGrory, C.R.N.P., Terrence Williams, B.S., Monica Williams, B.S., Edward J. Gracely, Ph.D., and Linda Stern, M.D. A Low- Carbohydrate as Compared with a Low-Fat Diet in Severe Obesity. N Engl J Med 2003; 348:2074-2081.

Gary D. Foster, Ph.D., Holly R. Wyatt, M.D., James O. Hill, Ph.D., Brian G. McGuckin, Ed.M., Carrie Brill, B.S., B. Selma Mohammed, M.D., Ph.D., Philippe O. Szapary, M.D., Daniel J. Rader, M.D., Joel S. Edman, D.Sc., and Samuel Klein, M.D. A Randomized Trial of a Low-Carbohydrate Diet for Obesity. N Engl J Med 2003; 348:2082-2090.

Houston, M. What your doctor may not tell you about Heart Disease. Grand Central Life & Style (2012).

Kraemer WJ, Volek JS, Clark KL, Gordon SE, Puhl SM, Koziris LP, McBride JM, Triplett- McBride NT, Putukian M, Newton RU, Häkkinen K, Bush JA, Sebastianelli WJ.

Influence of exercise training on physiological and performance changes with weight loss in men. Med Sci Sports Exerc. 1999 Sep;31(9):1320-9.

Schuenke MD, Mikat RP, McBride JM. Effect of an acute period of resistance exercise on excess post-exercise oxygen consumption: implications for body mass management. Eur J Appl Physiol. 2002 Mar;86(5):411-7. Epub 2002 Jan 29.

Tremblay A, Simoneau JA, Bouchard C. Impact of exercise intensity on body fatness and skeletal muscle metabolism. Metabolism. 1994 Jul;43(7):814-8.

van Gent RN, Siem D, van Middelkoop M, et al Incidence and determinants of lower extremity running injuries in long distance runners: a systematic review British Journal of Sports Medicine 2007;41:469-480.

 

Most women are afraid to lift weights like men because they think they will look bulky and like the women we see on the left hand pictures. It is time to demystify this idea and explain why this is impossible (provided than no hormones and/or anabolic steroids are used), and why strength training is key and a great ally to improve a number of parameters, including body composition.

Overuse of low-intensity training protocols by women is too common. Too much emphasis is placed on cardio, machine use, treadmills, bicycles, light loads, and too little emphasis is put on what will promote better physiological adaptations for increasing women’s functional capacity – strength training. If you want to bring more years into your life, you should start looking at strength training as one of the most effective anti-aging tools on Earth. There is no system in our body that is not influenced by strength training! Have I told you that it is cheaper than the creams you rub on your body every day?

I will divide this article into three parts. First, let’s highlight the myths of strength training for women, which were already addressed by Ebben & Jensen in 1998 in Strengthening for women: debunking myths that block opportunity. Second, let’s highlight its main benefits, and third, let’s explain why you will not look like Arnold Schwarzenegger.

1. MYTHS OF STRENGTH TRAINING FOR WOMEN

  •  Strength training will cause women to become big and heavy.The truth is that strength training helps to reduce body fat and increase lean mass. These changes may result in a slight increase in weight since the lean mass is more dense than fat (note: if this disturbs you throw the scale away and look more at yourself in the mirror!). Strength training will result in increased strength, no change or a decrease in the hip and waist perimeters and a slight increase in the perimeter of the upper body. Only women who are genetically predisposed for hypertrophy and who participate in high volume and intensity workouts may see substantial increases in the circumference of their limbs.
  • Women should use different training methods than men.Women are often encouraged to use machines and to do many repetitions slowly because they are afraid that the use of free weights, manual resistance, explosive movements or exercises that use their body weight as resistance will cause injury. In fact, there is no evidence suggesting that women are more likely than men to injure themselves during strength training. The most important factors to reduce the risk of injury are based on exercise technique and training individualization.
  • Women should avoid high intensity training or training with high loads.Women are usually encouraged to use smaller weights in their strength training (i.e., light dumbbells) but the problem is that these light loads are substantially below what is required to promote physiological adaptations. Women need to train at intensities high enough to promote adaptations in bones, muscles, cartilage, ligaments and tendons. When the intensity of the exercise is low, that is, when the stimulus is insufficient, the physiological benefits are minimal. To maximize the benefits of strength training, women should train close to their maximum. For women who have had children, imagine that this is what you have to “push” to get the greatest benefits.In short, there is no reason for women to train differently from men with regard to training intensity. If you intend to get different results, you need to leave aerobic classes and pink weights to start lifting real weights.

2. STRENGTH TRAINING BENEFITS FOR WOMEN

In addition to improving body composition (loss of fat mass and increase in lean body mass), strength training will help you:

  •  Increase bone remodeling. You will get stronger bones and reduce the risk of osteoporosis (LINK, LINK, LINK). Keep in mind that stronger bones can also result in total weight gain, but this is good, strong bones are a sign of health;
  • Strengthen the connective tissue. You will increase your joint stability and reduce the risk of injury (LINK). As in the previous point, same thing can happen regarding weight gain;
  • Increase functional strength for activities you enjoy or for your daily activities (e.g. playing with your kids, carrying grocery shopping, climbing stairs).
  • Increase self-esteem and confidence. A stronger body will make your mind stronger and unstoppable!
  • Fight the effects of metabolic syndrome and other common chronic diseases in our society, such as cardiovascular disease, type II diabetes, cancer, fibromyalgia, rheumatoid arthritis and Alzheimer’s disease (LINK, LINK).
  • Increase longevity in a healthy way. Strength training will potentiate the release of anabolic hormones that play an important role in tissue regeneration and anti- aging (LINK).

In summary, strength training has the potential to restore the shape of your glutes, the glow of your skin and the tonus of those parts of the body that you think is only possible through surgery, miracle supplements and advanced techniques of “muscle toning”. Strength training can also help you live the life of your dreams.

3. WHY I WILL NOT BECOME ARNOLD SCHWARZENEGGER?

arnold-schwarzenegger-6-claves-del-exito

 

Women have different physiological characteristics from men and this is the reason why women have greater difficulty in gaining muscle than men. As I said at the beginning of this article, if there are no hormones and/or anabolic steroids involved, it is very unlikely that women will look like men.

  •  Diferences in muscle fibersAlthough women have the same types of muscle fibers that men have (fast-twitch fibers and slow-twitch fibers), the amount of muscle fibers they have and their size is smaller. Remember that slow-twitch fibers (type I) are used primarily in endurance efforts whereas fast-twitch fibers (type II) are used primarily in rapid and explosive movements. In women, because they have 70-75% type I fibers, it becomes even more difficult to move loads at high speeds. This means that the potential for increasing the cross-sectional area of the muscle (i.e. muscle size) and for increasing the rate of force development is lower in females than in males.
  • Diferences in strength and powerThe average total body strength of a woman corresponds to about 60% of the average total body strength of a man. In average, upper body strength in women ranges from 25-55% of men’s upper body strength. Regarding lower body strength, it seems that women are stronger in relative terms. In average their capacity is 70-75% of what is observed in men. It is therefore not surprising that most women find it more difficult to lift weights with arms and upper body (e.g. push-ups and pull-ups) than with legs and lower body (e.g. squats and lunges).
  • Diferences in hormone levelsThe most obvious difference in the mechanisms that determine the adaptations to training of men and women is the sex hormone, testosterone. Both men and women produce testosterone, the difference is that testosterone concentrations in men are 10 to 20 times higher than in women! It appears that women are more dependent on pituitary secretion from growth hormone and other growth factors to help mediate changes in muscle, bone and connective tissue. In fact, although strength training adaptations do not occur in the same way, it has been reported that women have higher bioavailable concentrations of growth hormone at rest than men. Fortunately, strength training and metabolic resistance training can also increase growth hormone levels.Also, if you begin to lift weights in a progressive manner, you will continue to maintain your femininity, you will not grow a mustache, beard or hair in your chest. You will not get bigger or full of muscles. On the contrary, you will get leaner, stronger, younger, smarter and much more attractive to the opposite sex. But do not be fooled, to get the greatest benefits in training, you need to work hard and realize that it takes serious effort to induce the metabolic adaptations you seek (e.g. improving body composition and biological aging). This does not happen overnight. You will need time, consistency and discipline. There are no miracle pills.

In conclusion, before beginning a strength training program, be aware that you must have movement competency in the first place. Just as you would not begin to calculate derivatives in mathematics before you know how to add and subtract, it also makes no sense to start lifting heavy loads if you have restrictions and/or asymmetries in your movement profile. The quality of movement is the foundational support for functional strength development so this “ingredient” will always have to come first.

For a graphic resource check out this nice infographic from Positive Health Wellness.

See you soon and enjoy 🙂

Pedro Correia

References

Ciccolo Joseph T, Carr Lucas J, Krupel Katie L, Longval Jaime L. The Role of Resistance Training in the Prevention and Treatment of Chronic Disease. American Journal of Lifestyle Medicine July/August 2010 vol. 4 no. 4 293-308.

Cussler EC, Lohman TG, Going SB, Houtkooper LB, Metcalfe LL, Flint-Wagner HG, Harris RB, Teixeira PJ. Weight lifted in strength training predicts bone change in postmenopausal women. Med Sci Sports Exerc. 2003 Jan;35(1):10-7.

Ebben WP, Jensen RL. Strength training for women: debunking myths that block opportunity. Phys Sportsmed. 1998 May;26(5):86-97. doi: 10.3810/psm.1998.05.1020.

Hurley BF, Hanson ED, Sheaff AK. Strength training as a countermeasure to aging muscle and chronic disease. Sports Med. 2011 Apr 1;41(4):289-306. doi: 10.2165/11585920-000000000-00000.

Kraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance exercise and training. Sports Med. 2005;35(4):339-61.

Nickols-Richardson SM, Miller LE, Wootten DF, Ramp WK, Herbert WG. Concentric and eccentric isokinetic resistance training similarly increases muscular strength, fat-free soft tissue mass, and specific bone mineral measurements in young women. Osteoporos Int. 2007 Jun;18(6):789-96. Epub 2007 Jan 31.

Stone MH. Implications for connective tissue and bone alterations resulting from resistance exercise training. PubMed PMID: 3057317.

Winters KM, Snow CM. Detraining reverses positive effects of exercise on the musculoskeletal system in premenopausal women. J Bone Miner Res. 2000 Dec; 15(12):2495-503.

Zatsiorsky V., Kraemer, W. Science and Practice of Strength Training 2nd Edition. Human Kinetics (2006).

 

If your grandfather is a normal person, it is very likely that he has been to the doctor many times, that he is on medication, that he does not hear very well and that he does not have the same locomotion capacity and reasoning that he had some years ago.

Doctors say this is “normal” and typical of the advancing age. They also prescribe drugs based on the belief that this will improve the quality of life of these people. I do not say that this is not necessary in some cases, but I do not believe that this is the best approach to increase health span. Although they “breathe” I think that they deserve better and more.

More than two years ago, a piece in a portuguese newspaper stated that the Portuguese lived longer and longer but less healthy. The piece also mentioned: “Portuguese women have one of the longest life expectancy in the world, but, paradoxically, enjoy far fewer healthy years than women from the best-ranked countries in Europe.”

When reading the piece, the first thing I thought was: we have to be really stupid, because even with the daily advances of medicine and scientific knowledge, we have not yet been able to understand what are the causes behind this SICK LONGEVITY. The problem is not the advancing years, the problem lies in nutrition and exercise related advice we hear every day (especially in hospitals), which is simply erroneous. If prevention campaigns and the information leaflets in hospitals were really supported by scientific evidence, one would not witness so many people suffering from chronic pain, diabetes, heart disease, osteoporosis, sarcopenia, autoimmune diseases and cancer.

Everyone recognizes that physical exercise is key to optimal body function (our brain and body did not develop while sitting on our asses), and that, unlike drugs, has a positive and self-regulating impact on the various systems of the human body.
Exercising is more effective on improving your health than any patented medicine.

“But I walk an hour every day”

Let me tell you one thing, walking is the least you can do to keep your body working. If you tell me that is either walking or lying back on the couch eating ice cream, then you better walk. But if you tell me that you want to live a healthy life until you die, maintain your autonomy, decrease the risk of falls, increase self-confidence, sleep better, recover faster from an injury and not be part of the statistics we saw above, then I recommend you start seriously thinking about lifting weights and engaging in strength training. Walking will not give you, even by shadows, the same benefits as strength training.

Another thing, if you are one of those people with cardiovascular disease, your doctor (or some Dr. from Google) has probably told you that walking is important to improve your cardiovascular health. The problem is that walking will not help you much. The lack of aerobic capacity is not a risk factor for heart disease, a sedentary lifestyle is! This means that you may have a huge aerobic capacity and a heart disease at the same time. In fact, according to this study published in the 2006 American Heart Association Journal (LINK), to this one published in 2008 in the European Heart Journal (LINK) and to this one published in the Mayo Clinic Proceedings (LINK) in 2012, marathoners are those who appear to be at increased risk of developing cardiovascular disease.

Furthermore, according to the cardiologist Henry A. Solomon in the book “The Exercise Myth”, cardiovascular health refers to the absence of heart and blood vessel disease, and not to an individual’s ability to do a certain amount of physical work. According to Dr. Solomon, your cardiac health is determined by the condition of various structures of the heart, including the heart muscle, the valves, the special cardiac tissues that carry electrical impulses and the coronary arteries. So, do not expect exercise to “clean” what you practice in your daily diet.

The cardio craze came about in the late 60’s / early 70’s through Dr. Kenneth Cooper, the person who designed the Cooper test for US military use. It was roughly from this moment on that VO2max (a measure of aerobic capacity) was “elected” the holy grail of physical fitness. Although relevant for performance and longevity, VO2max is not the only marker of physical fitness. Strength in its various forms has been more strongly correlated with increased longevity than VO2max. While strength training can increase both functional strength and aerobic capacity, the typical cardio training will not make you stronger and will only slightly “at best” increase your VO2max.

Why Strength Training?

Because you tend to lose strength and power as you age, and because several studies have shown that loss of strength and muscle mass are associated with increased mortality (LINK, LINK, LINK). Fortunately, lifting weights is the best stimulus to counteract this trend and to increase our functional capacity. Under normal conditions, strength peaks between the ages of 20 and 30, remaining relatively stable or decreasing slightly over the following 20 years. But this is dependent, of course, of what one does in training.

It is in the sixth decade of life that decreases in strength are quite pronounced. According to several longitudinal studies, declines in muscle strength are around 15% between 60-70 years of age and 30% after age 70. Most reasons relate to the loss of muscle mass, pronounced loss of fast-twitch muscle fibers, decreased endocrine function, loss of tissue mobility / elasticity and cell dehydration. All of these can be minimized by following a proper strength training program.

Yes, it is possible to start strength training at any age, I know people who started training at 50, 60 and over 80, it’s all a matter of mindset and willpower. Also, you need to train according to your needs as opposed to the convenience of most gyms (i.e. spending hours on the treadmill / elliptical / bike, going through all the machines and ignore training with free weights) where supervision, tutoring and skill learning are dismissed.

Does this mean that I should get my grandparents to lift Olympic bars and weights without any criteria? Of course not, that would not be very smart. To get the most benefit of lifting weights you have to walk a path and create a solid movement base. You have to be screened and assessed for movement quality and physical parameters. Preferably guided by a fitness professional or personal trainer knowledgeable in movement and strength training science.

Listen, your doctor’s opinion might be highly valuable, however remember the following: 1) your doctor is not a specialist in movement (which is ok, they can not be trained in everything); 2) your doctor has no experience training people (which is also ok, it’s not their job); 3) your doctor probably does not even know how to lift weights or to move well (this is obviously not ok!). In other words, just as you would not ask advice on surgery techniques from strength coaches, you should also not ask advice on training methodologies and forms of physical exercise from surgeons.

Oh, and before you tell me that I’m being fundamentalist and suggesting that you should not train other physical abilities (such as stability, mobility, endurance, speed, agility, motor coordination, power), allow me to conclude with the following observation: ideally, the training program of any human being on the planet should always be the one that induces the adaptations necessary to fulfill his /her personal goals.

The key word here is adaptation! The more adapted you are the better prepared you will be to face any situation. Adults are free to do whatever they want in life. Everyday we make decisions and choices and those decisions matter. My goal is to increase longevity and live until the last days of my life feeling great and strong.
What’s yours?

See you soon!

Pedro Correia

References

Möhlenkamp S, Lehmann N, Breuckmann F, Bröcker-Preuss M, Nassenstein K, Halle M, Budde T, Mann K, Barkhausen J, Heusch G, Jöckel KH, Erbel R; Marathon Study Investigators; Heinz Nixdorf Recall Study Investigators. Running: the risk of coronary events : Prevalence and prognostic relevance of coronary atherosclerosis in marathon runners. Eur Heart J. 2008 Aug;29(15):1903-10. doi: 10.1093/eurheartj/ehn163. Epub 2008 Apr 21.

Neilan TG1, Januzzi JL, Lee-Lewandrowski E, Ton-Nu TT, Yoerger DM, Jassal DS, Lewandrowski KB, Siegel AJ, Marshall JE, Douglas PS, Lawlor D, Picard MH, Wood MJ. Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston marathon. Circulation. 2006 Nov 28;114(22): 2325-33. Epub 2006 Nov 13.

O’Keefe JH, Patil HR, Lavie CJ, Magalski A, Vogel RA, McCullough PA. Potential adverse cardiovascular effects from excessive endurance exercise. Mayo Clin Proc. 2012 Jun;87(6):587-95. doi: 10.1016/j.mayocp.2012.04.005.

Rantanen T, Harris T, Leveille SG, Visser M, Foley D, Masaki K, Guralnik JM. Muscle strength and body mass index as long-term predictors of mortality in initially healthy men. J Gerontol A Biol Sci Med Sci. 2000 Mar;55(3):M168-73.

Ruiz JR, Sui X, Lobelo F, Morrow JR Jr, Jackson AW, Sjöström M, Blair SN. Association between muscular strength and mortality in men: prospective cohort study. BMJ. 2008 Jul 1;337:a439. doi: 10.1136/bmj.a439.

Takata Y, Ansai T, Soh I, Akifusa S, Sonoki K, Fujisawa K, Awano S, Kagiyama S, Hamasaki T, Nakamichi I, Yoshida A, Takehara T. Association between body mass index and mortality in an 80-year-old population. J Am Geriatr Soc. 2007 Jun;55(6):913-7.

Zatsiorsky V., Kraemer, W. Science and Practice of Strength Training 2nd Edition.
Human Kinetics (2006).

 

Several lines of evidence suggests that mitochondrial dysfunction is associated with sarcopenia (loss of strength and muscle mass in aging). In every cell of our body there are hundreds or thousands of mitochondria, they exist in greater quantity in the most active organs and tissues (muscles, heart and brain). The reason we age faster derives from the constant injuries and insults inflicted to the mitochondria. Chronic stress, lack of sleep, poor eating choices, lack of exercise (particularly strength training), alcohol, tobacco, and exposure to pollutants are just a few examples of how our lifestyle can influence the function of these small structures.

Mitochondria are the organelles responsible for energy production in our body. If you feel always tired, if you experience memory loss, if you have frequent muscle pain and if you are one of those people taking medications for cholesterol, hypertension, diabetes and other chronic diseases, it is very likely that your mitochondria are not in “great shape”. But let’s look at some evidence.

This study may be considered revolutionary because of its highly relevant findings regarding the benefits of strength training in older people. This study was published in 2007 and was the first study human study to demonstrate that strength training can reverse the aging process at molecular level. If it was a drug or a food supplement demonstrating these effects, I think everyone already knew.

Sample

The researchers recruited 25 healthy elderly people (mean age 68 years), who already did some type of physical exercise (walking, gardening, tennis, golf, cycling) three to four times a week, and 26 young adults (mean age 24 years) relatively inactive, some of them participating in recreational activities.

The authors selected relatively active older adults and sedentary young adults in order to study the aging process on healthy elderly and not just the putative aging effect of physical inactivity. All older subjects underwent a thorough screening process before being admitted to the study to ensure that other factors (e.g. metabolic diseases) would alter mitochondrial function.

All subjects completed a medical evaluation before participating in the study. Exclusion criteria were: evidence of heart disease (by history and sub-maximal graded exercise test); hypertension; chronic obstructive pulmonary disease; diabetes mellitus; renal insufficiency; orthopedic injury and smoking. None of the subjects had previously participated in a structured resistance training program.

Training Program

Subjects performed resistance exercises with supervision on two nonconsecutive days of the week (monday/thursday or tuesday/friday) for 26 weeks (six months). The subjects performed twelve different exercises including chest press, leg press, leg extension, leg flexion, shoulder press, lat pull-down, seated row, calf raises, crunches, back extensions, bicep curl and triceps extension.

Subjects initially started with a set of 50% of 1 maximal repetition (1RM), and gradually increased to three sets at 80% of their 1RM during the intervention period. Subjects tested their 1RM for every exercise every two weeks, and training loads were adjusted to maintain 80% of their 1RM.

Muscular Biopsy

All younger subjects (N = 26) underwent a muscle biopsy (incision and extraction of a small part of muscle) from the vastus lateralis (thigh muscle) before and after the 26-week study. The elderly subjects (= 25) did their biopsies before the study and after (N = 14) of the study. Muscle RNA (ribonucleic acid) was analyzed to determine age-related gene expression variation.

Results

The authors identified 596 genes that were differentially expressed between the two age groups. Of the 596 genes, the researchers identified 179 associated with age and exercise that showed a remarkable reversal in their expression profile after six months of resistance training. This literally means that resistance training not only can slow down but also reverse the aging process at the genetic level. The genetic expression of the elderly individuals became similar to those of the younger group. The researchers also noted that mitochondrial dysfunction (closely related to physical inactivity) began to reverse after six months of training.

As for muscular strength, results were as expected, that is, the ones who strength trained got stronger. The initial gap of 59% in maximal isometric strength in older people vs. young adults was reduced to 38% after six months of resistance training.

Conclusions

Nowadays, it is widely accepted that physical exercise is associated with a decrease in morbidity and mortality in humans. This is not a belief. What people probably do not know is that there are forms of physical exercise that are more effective in increasing strength and longevity. This study demonstrated for the first time that resistance training can reverse age-related aspects at the gene level. Yes, you are reading well, resistance training can reverse aging at the molecular level!

The fact that older people got stronger was no surprise to me and certainly not for fitness professionals. It is not uncommon for older people to begin their training with minimum weights and, in a short time, evolve to loads equal to or greater than those in their twenties. It’s all about dedication, consistency and method.

Over the years, personal trainers and fitness professionals have been preaching their clients / athletes about the importance of physical exercise in improving health. This message, in my opinion, has not been well perceived by most people. Understanding the notion that movement and physical exercise is as important as the food they eat every day is, unfortunately, still lacking.

In short, this fascinating study is basically telling us that it is within our power to increase health and longevity. In this case, the “fountain of youth” is something we know and something that is relatively accessible to everyone – Strength Training.

However, for these benefits to occur, people have to be willing to work hard and with consistent effort, something rare in our “all in moderation” oriented society. Most people are in search of a miraculous pill and rather rely on faith than doing something for themselves. Therefore, I believe that only focused individuals and those who follow these principles in training (and in life) will end up having the most benefits. Things will not happen by chance, certainly.

See you soon!

Pedro Correia

References

Melov S, Tarnopolsky MA, Beckman K, Felkey K, Hubbard A (2007) Resistance Exercise Reverses Aging in Human Skeletal Muscle. PLoSONE 2(5): e465. doi:10.1371/ journal.pone.0000465

 

The Swing exercise is the foundation of hardstyle kettlebell training methodology and an essential exercise in our training programs at The Strength Clinic. The hardstyle Swing is an explosive movement characterized by a vigorous and complete extension of the knees and hips (in the top position) preceded by near maximal hip flexion and slight knee flexion (in the bottom position). The Swing is known for its effectiveness in improving performance in daily life activities as well as performance of athletes of the most varied modalities, from long distance runners to combat sports, among others. We can point out five reasons that make the hardstyle kettlebell Swing an exercise of choice for athletic development:

  1.  Strength. The acceleration and deceleration component inherent to the Swing induces important adaptations in the power production capacity despite the relatively light loads used. Reminding Newton’s second law (force = mass x acceleration), it is possible to increase force acting on a given system by increasing acceleration without increasing mass. In this case, the real load manipulated during some moments of the Swing performance will exceed the weight in Kg of the kettlebell, where peak forces generated can be up to 10 times more. This allows for significant maximal strength gains especially in the posterior chain;
  2.  Power. Due to its explosive nature based on a fundamental movement pattern (i.e. “hip hinge”, used in deadlift exercise). The vigorous extension of the hips and knees is at the base of any explosive athletic movement. The Swing not only allows you to work explosive strength, but also allows you to do it in a cyclical and repetitive way, and also in a very safe way. This feature constitutes an advantage of the kettlebell Swing in terms of benefit / risk, when compared to the Olympic movements like the Snatch or the Clean for power development. The Swing is not only less technically complex to learn, it allows greater number of repetitions without fatigue compromising (in a dangerous way) technical execution;
  3.  Trunk stability and rotational strength. The biofeedback offered by holding a kettlebell and the need to balance the forces generated by the acceleration and deceleration of the kettlebell, induces a marked activation of the stabilizing muscles of the trunk and shoulder joints. When performed with one hand, the Swing further accentuates muscle activation in a crossed chain fashion due to the anti-rotational component created. This type of rotational power generation manifests itself in the most varied sports movements, such as: the golf swing; the serve, forehand and backhand stroke in tennis; shooting in handball; shooting and serve in volleyball; shooting and kicking in soccer; throwing events in track and field athletics; etc;
  4.  Muscle and cardiovascular endurance. Due to its particular design, the kettlebell Swing allows repetition of explosive movements with maximum or near maximum acceleration. This possibility of safe repetition with an additional load delivers significant muscle and cardiovascular endurance adaptations;
  5.  Fat loss. Because it entails the stimulation of large amounts of muscle mass at a high intensity and repetitive way, the kettlebell Swing induces high metabolic stress levels. This metabolic stress results in increased oxygen consumption in the subsequent hours (i.e., increased calorie expenditure due to increased metabolism), thus contributing greatly for fat loss.

Indeed, the inclusion of the kettelbell Swing is a wise choice when structuring a well-rounded training program. The Swing is also highly versatile in terms of programming. By combining different loads, number of repetitions, rest periods and variations of the exercise (e.g. two-handed Swings, one-handed Swings, double Swings, dead stop Swings), one can easily shift the pointer in order to work on specific adaptations of the strength continuum (i.e. from the maximum strength end to the muscular endurance end) as well as on the various energy systems. And all this in a very safe way!

A 12-week fat loss program suggestion

Get a kettlebell (at least 16kg for women and 20kg for men) and have it in your living room or bedroom. Learn how to perform the hardstyle swing exercise with a certified instructor. Every day, whether you train in the gym or not, perform 5 sets (spread throughout the day according to your own convenience) of 20 swings during the first week, 25 swings during the second week, 30 swings during the third week and 35 swings during the fourth week. On the second month repeat the process with a kettlebell at least 4kg heavier, and on the third month with a kettlebell 8kg heavier. At the end of 12 weeks rejoice with the results!

Swing and enjoy…! 🙂

Nuno Correia